| View previous topic :: View next topic |
| Author |
Message |
Ferre Cannabis Sacrament Minister.


Joined: 14 Apr 2003 Posts: 7295 Location: Amsterdam
|
Posted: Tue Apr 19, 2005 2:32 pm Post subject: Health Canada has approved Sativex(R) |
|
|
| Quote: |
Attention Business/Health Editors:
Health Canada first to approve a novel cannabis derived pharmaceutical treatment for people with multiple sclerosis
TORONTO, April 19 /CNW/ - Health Canada has approved Sativex(R) (Cannabis
sativa L. extract) a new drug developed as adjunctive treatment for the
symptomatic relief of neuropathic pain in adults with multiple sclerosis (MS).
Canada becomes the first country in the world to approve Sativex, a novel
prescription pharmaceutical product derived from components of the cannabis
plant shown to have therapeutic properties. Sativex is administered via a
spray into the mouth.
Health Canada has approved Sativex with conditions, under the Notice of
Compliance with Conditions (NOC/c) policy. This authorization reflects the
promising nature of the clinical evidence which will be confirmed with further
studies. Products approved under Health Canada's NOC/c policy, have
demonstrated promising benefit, are of high quality and possess an acceptable
safety profile based on a benefit/risk assessment for the approved use.
"Effective pain control and management are extremely important in a
disease like MS," said Dr. Allan Gordon, Neurologist and Director of the
Wasser Pain Management Centre, Mount Sinai Hospital, Toronto, Ontario. "The
approval of Sativex in Canada reflects the urgent need for additional
treatment options in the field of neuropathic pain in MS."
Neuropathic pain
Pain is a common symptom of MS occurring in up to 86 per cent of people
with MS.(1) Neuropathic or nerve pain can occur spontaneously or can be
provoked by touch, temperature or movement. It is estimated that 50 per cent
of people with MS suffer from chronic neuropathic pain.(2)(3)(4) The most
common descriptions of neuropathic pain are of freezing, cold or burning
sensations usually of the limbs and most often of the lower extremities.(5)
Many individuals with neuropathic pain respond inadequately to current
treatment options.(6)(7)
"It's hard to explain to someone who has never felt this type of pain.
It's like being plugged into an electric socket all the time," said Steve
Walsh, who suffers from MS and has lived with neuropathic pain for five years.
"At times, putting on clothes or anything touching me can be too much to
take," he added.
Data demonstrates efficacy
While there is no complete cure for MS or neuropathic pain, a
double-blind placebo controlled parallel group study demonstrated that Sativex
provided significantly greater pain relief than placebo. Sativex also
significantly reduced pain-related sleep disturbance.(8 )
Principal components
A product resulting from the pioneering research efforts of UK-based
GW Pharmaceuticals plc and marketed in Canada by Bayer HealthCare,
Pharmaceuticals Division, Sativex is the first product indicated in Canada as
adjunctive treatment for the symptomatic relief of neuropathic pain in MS.
Its principal active cannabinoid components are delta-9-
tetrahydrocannabinol (THC) and cannabidiol (CBD).(8 ) The ratio of THC to CBD
in Sativex is 2.7 mg : 2.5 mg per spray, ensuring a standardized dose is
delivered each time it is used.
"The approval of Sativex is good news for the Canadian MS community.
People living with MS and neuropathic pain need new options to address their
pain. Sativex will likely be welcomed by the many people with MS, whose
quality of life has been further compromised with neuropathic pain," said Dr.
William J. McIlroy, National Medical Advisor, MS Society of Canada.
How Sativex works
Sativex is administered through a spray pump under the tongue or on the
inside of the cheek, providing reliable, self-administered pain relief. The
spray formulation allows for more flexible dosing than an oral tablet, well
suited to the variable nature of neuropathic pain experienced by people with
MS.
"Because Sativex is designed for self-administration, this allows for
flexible dosing and puts the patient in control of their pain," said Dr.
Gordon. "This is very important since pain severity varies between different
patients and even in the same patient at different times."
Sativex and side-effects
In clinical trials, the most frequent side-effects included nausea,
fatigue, dizziness and application site reactions. Side-effects were usually
mild or moderate in severity and often resolved with down-titration or
interruption of treatment.(8 )
Sativex is expected to be available through Canadian pharmacies by late
Spring 2005.
Multiple sclerosis (MS) in Canada(9)
MS is a disease of the central nervous system and is the most common
neurological disease affecting young adults in Canada. Approximately
50,000 Canadian men and women have the disease and each day approximately
three more people are diagnosed. MS is most often diagnosed in people between
the ages of 20 to 40 years of age.
About Bayer HealthCare AG
Bayer HealthCare AG, a subsidiary of Bayer AG, is one of the world's
leading, innovative companies in the health care and medical products
industry. In 2004, the Bayer HealthCare subgroup generated sales amounting to
some 8.5 billion Euro.
The company combines the global activities of the divisions Animal
Health, Biological Products, Consumer Care, Diabetes Care, Diagnostics and
Pharmaceuticals. Bayer HealthCare employed 35,300 people worldwide in 2004.
Bayer HealthCare's aim is to discover and manufacture innovative products
that will improve human and animal health worldwide. The products enhance
well-being and quality of life by diagnosing, preventing and treating disease.
This news release contains forward-looking statements based on current
assumptions and forecasts made by Bayer Group Management. Various known and
unknown risks, uncertainties and other factors could lead to material
differences between the actual future results, financial situation,
development or performance of the company and the estimates given here. These
factors include those discussed in our public reports filed with the Frankfurt
Stock Exchange and with the U.S. Securities and Exchange Commission (including
our Form 20-F). The company assumes no liability whatsoever to update these
forward-looking statements or to conform them to future events or
developments.
About GW Pharmaceuticals plc
GW Pharmaceuticals plc is licensed by the UK Home Office to undertake a
pharmaceutical research and development program to develop non-smoked
cannabis-based prescription medicines. GW's shares are publicly traded on AiM,
a market on the London Stock Exchange.
Full details of GW and the company's clinical trials program can be found
at www.gwpharm.com. GW's clinical research program is being carried out by a
team of pharmaceutical professionals experienced in drug development and, in
particular, the development of plant-based medicines and drug delivery
systems.
This news release may contain forward-looking statements that reflect
GW's current expectations regarding future events, including the clinical
development and regulatory clearance of its products. Forward-looking
statements involve risks and uncertainties. Actual events could differ
materially from those projected herein and depend on a number of factors,
including (inter alia), the success of GW's research strategies, the
applicability of the discoveries made therein, the successful and timely
completion of clinical studies, including with respect to Sativex and GW's
other products, the uncertainties related to the regulatory process, and the
acceptance of Sativex and other products by consumers and medical
professionals.
References:
------------------------
(1) Ehde DM et al. Multiple Sclerosis 2003; 9; 605-611.
(2) Archibald CJ, et al. Pain 1994; 58:89-93.
(3) Sketris IS, et al. Clinical Therapeutics 1996; 18(2):303-318.
(4) Moulin DE, et al. Neurology 1988;38:1830-1834.
(5) Multiple Sclerosis International Federation
www.msif.org/print.rm?id=10188
(6) Harden N and Cohen M. Journal of Pain Symptom Management 2003;
25 (5 Suppl): S12-S17.
(7) New Directions in Neuropathic Pain: Focusing Treatment on Symptoms
and Mechanisms. Royal Society of Medicine Press Ltd.: 2000.
(8 ) Sativex Product Monograph - April 2005
(9) www.mssociety.ca
For further information: IN WESTERN CANADA, PRAIRIES:
Sousie Tsotskos, Cohn & Wolfe, TEL: (416) 324-2069 ext. 4066,
sousie_tsotskos@ca.cohnwolfe.com; IN ONTARIO: Alanna Fox, Cohn & Wolfe,
TEL: (416) 324-2069 ext. 4078, alanna_fox@ca.cohnwolfe.com; IN QUEBEC:
Sylvie Tessier, Cohn & Wolfe, TEL: (514) 845-2257 ext. 232,
sylvie_tessier@mtl.cohnwolfe.com; IN MARITIMES, NEWFOUNDLAND: Kate
Morrison, Cohn & Wolfe, TEL: (416) 324-2069 ext. 4059,
kate_morrison@ca.cohnwolfe.com; IN EUROPE: Mark Rogerson for GW
Pharmaceuticals, TEL: 011-44-1980-557-000, CELL: 011-44-7885-638-810,
mvlrog@aol.com; BAYER INC.: Lori Ann Horrigan,
Tel: (416) 240-5252 or 1-800-440-5473, lori-ann.horrigan.b@bayer.com
http://www.newswire.ca/en/releases/archive/April2005/19/c7215.html?view=print
|
_________________ █ Please read the Board Rules and Posting, and you
█ Radio Free Amsterdam
People who know truth, speak truth.
Those who don't, quote scriptures. |
|
| Back to top |
|
 |
Pepper Cannabis Sacrament Minister


Joined: 30 Oct 2003 Posts: 528 Location: Earth
|
Posted: Tue Apr 19, 2005 3:10 pm Post subject: |
|
|
| This is good news but on the other hand could be used to justify the closing of compassion clubs in Canada. |
|
| Back to top |
|
 |
Ferre Cannabis Sacrament Minister.


Joined: 14 Apr 2003 Posts: 7295 Location: Amsterdam
|
Posted: Tue Apr 19, 2005 3:25 pm Post subject: |
|
|
Yes, that's a thought I share with you bro. Let's hope this won't happen. _________________ █ Please read the Board Rules and Posting, and you
█ Radio Free Amsterdam
People who know truth, speak truth.
Those who don't, quote scriptures. |
|
| Back to top |
|
 |
Pepper Cannabis Sacrament Minister


Joined: 30 Oct 2003 Posts: 528 Location: Earth
|
Posted: Tue Apr 19, 2005 3:57 pm Post subject: |
|
|
| Unfortunately, it already has. GW has bought significant stock in Prarie Plant systems, the only company liscensed to grow marijuana on a large scale. They have also hired some of the luminaries in the pot movement that now have been silenced on the issue. Previously these people were leading the fight against a government monopoly. The biggest fear is that seeds will become illegal now that there is a legal source of cannabis. |
|
| Back to top |
|
 |
Pepper Cannabis Sacrament Minister


Joined: 30 Oct 2003 Posts: 528 Location: Earth
|
Posted: Tue Apr 19, 2005 6:08 pm Post subject: |
|
|
This from cannabisculture.com
CANADA BECOMES SATIVEX COUNTRY
GW’s plant-based medicine approved for pharmacies
By Nigel Olson
Canada is the first country in the world to license a plant-based cannabinoid pharmaceutical medicine, Sativex, created by GW Pharmaceuticals and marketed in conjunction with Bayer.
Sativex is a combination of plant-derived delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). The ratio of THC to CBD in Sativex is 2.7 mg to 2.5 mg per spray, which ensures a standardized dose is delivered each time it is used. It’s administered via a spray pump which places Sativex spray under the tongue or on the inside of the cheek.
The spray formulation allows for more specific dosing than oral tablets, well-suited to the variable nature of neuropathic pain experienced by people with Multiple Sclerosis (MS), which is the main target patient audience for Sativex.
GW Pharmaceuticals is still waiting for regulatory approval of Sativex in England, where the product was developed and where it was first submitted for approval two years ago.
Canadian approval, which took less than a year, is expected to expedite UK approval. Sativex is expected in Canadian pharmacies by June, 2005.
MS is a disease of the central nervous system- the most common neurological disease affecting young adults in Canada. Approximately 50,000 Canadian men and women have MS, and approximately three more people are diagnosed each day, mostly in people between the ages of 20 to 40 years of age.
Pain is a common symptom of MS occurring in up to 86 per cent of people with MS. Neuropathic or nerve pain occurs spontaneously or can be provoked by touch, temperature or movement. Half the people with MS suffer from chronic neuropathic pain, which is described by patients as freezing cold or burning sensations in the limbs, most often in the legs.
“It’s hard to explain to someone who has never felt this type of pain. It’s like being plugged into an electric socket all the time,” said Steve Walsh, who used Sativex in clinical trials and who suffers from MS. “At times, putting on clothes or anything touching me can be too much to take.”
According to Dr. Allan Gordon, Director of the Wasser Pain Management Centre in Toronto, “Effective pain control and management are extremely important in a disease like MS. The approval of Sativex in Canada reflects the urgent need for additional treatment options in the field of neuropathic pain in MS.”
A HAPPY GUY
Dr. Geoffrey W. Guy is the pioneering physician and pharmaceutical developer who created GW and Sativex. When the Canadian approval of Sativex was announced on April 19, 2005, Guy breathed a sigh of relief.
Ever since he embarked on his quest to make a plant-based cannabis medicine, his company has come under attack from marijuana activists who asserted that he was seeking a medical cannabis monopoly.
The same activists attacked Guy for partnering with Bayer, a German company which some criticize because it was an industrial participant in Nazi Germany, along with thousands of other companies such as BMW and IBM.
GW also faced a copycat syndrome. After his company had spent millions of dollars researching natural cannabinoids and cannabinoid medicines, and finding out how hard it was to get chemically-oriented regulators to approve them, other companies began to adopt or modify his approach, hoping to cash in on the naturally-derived, controlled dose, pharmaceutical cannabinoid medicine market at his expense.
Among the copycatters are Canadian company Cannasat, configured in 2004 and which has yet to create its own medicine, and Solvay Pharmaceuticals, which sought to market a single synthetic cannabinoid, Dronabinol, as an inhaler-delivered medicine.
Single molecule synthetics like Dronabinol, which is marketed as Marinol, have been found to be ineffective by many medical pot patients, who say they’d rather smoke cannabis than use Marinol pills.
In some cases, the side effects of Marinol have caused serious problems for patients, and many researchers say that the single-cannabinoid approach, especially when the cannabinoid is a synthetic one, does not work well for most patients.
Guy began his quest to develop natural cannabis medicines in 1998, when the British physician and pharmaceutical products developer became the first person in recent memory to receive a UK government license to grow marijuana.
Guy enthusiastically contacted Cannabis Culture to announce Canadian approval for Sativex.
To create Sativex, Guy grew massive amounts of totally-organic marijuana. In 1999, he began growing 25,000 plants in specially-built, well-guarded greenhouses in southern England.
Since then, he has grown more than 300,000 “numbered, registered plants,” most of which have been selectively bred to produce unusually high percentages of one of many active ingredients in whole marijuana- cannabinoids- that Guy extracts for use in his pharmaceutical cannabis medicines.
Guy’s plants are proprietary strains of cannabis originally procured from Dutch marijuana research company Hortapharm. Dr. Guy doesn’t personally use marijuana, booze or coffee, but his company cultivates more marijuana than anyone else in the world.
His plants grow in massive, pristine greenhouses segregated into computer-controlled micro-climates containing virtually mono-cannabinoidic plants that produce high percentages of these target cannabinoids: THC, CBD, THC-V, CBC, CBD-V, CBG or CBN. Currently, these cannabinoids are the ones thought to possess the most significant medical value.
Guy says he produces many tons of totally-organic, inspected, quality-controlled dried buds each year, and has amassed a comprehensive horticultural-pharmaceutical cannabis database while also extracting and testing cannabinoids. He is an expert on cloning techniques, soil, plant pests (thrips and spider mites are the worst pests, he says), humidity, and other technical factors that make commercial pot growing a science and an art.
Guy’s publicly-traded company has developed three types of medicine made from cannabis extracts: a high-THC extract called Tetranabinex, a mostly-CBD extract called Nabidiolex, and the 51-49% mixture of CBD and THC, called Sativex.
These drugs are the results of medical research GW began in 1998. Almost single-handedly, GW’s scientists and doctors have proven to skeptical scientists and regulators that marijuana’s medical benefits- described derisively as “merely anecdotal” and “unproven” by drug warriors- are scientifically verifiable.
The extracts give unusually safe and effective relief for patients with MS, chronic pain, and other serious conditions. In some cases, GW proved, cannabinoids are the ONLY medicine that provides relief. The company is elated on getting approval for Sativex, but is also seeking approval for natural cannabinoid medicines that will treat arthritis, schizophrenia, appetite disorders, nerve damage, and glaucoma.
Guy’s scientific team includes the world’s top cannabis researchers, including Dr. Raphael Mechoulam and Dr. Roger Pertwee.
BAYER THE BEAR?
In May, 2003 Guy sold marketing rights for Sativex to Bayer, a major German pharmaceutical company. Guy viewed Bayer’s interest as proof that cannabis medicines had finally become legit.
Guy’s critics, especially Pot-TV host and writer-activist David Malmo-Levine, saw it otherwise, alleging Bayer is an unethical company, and impugning GW because it affiliated with Bayer.
Malmo-Levine and other GW critics believe smoked cannabis is safe, effective medicine, that cannabis pharmaceutical products are not needed, and that pharmaceutical research, patents and products are part of a capitalist-prohibitionist conspiracy that will eventually prevent black market growers and users from having access to raw cannabis for self-medication.
Dr. Guy views Malmo-Levine’s criticisms as “one-sided attacks” rather than “fair reporting.”
“It must be noted that [Malmo-Levine] never talked to me before he started publishing articles accusing us of being an evil company,” Guy said. “That is not how a professional journalist operates, is it? Our company created medicines that work for patients who had no relief from other medicines. We submitted a strong dossier to the Medicines and Healthcare Products Regulatory Agency (MHRA) in England, so patients can finally get effective cannabinoid products from their pharmacists, and be reimbursed by their health insurance. We hope to have MHRA approval very soon, and we now have Canadian approval. We are working on getting approval in America, a very tough place due to their prejudice against recreational cannabis, but we will do it. We are helping thousands and potentially millions of patients. How many patients are our critics helping?”
GW is not alone in the race to develop cannabis medicines, but Guy says his company’s use of organically-produced natural cannabis extracts is innovative, proprietary and medically efficacious.
Other companies, such as Solvay, create and market synthetic products like Marinol, a chemical THC analog, which has long been criticized by because its synthetic “single cannabinoid” approach can produce negative side-effects while failing to relieve symptoms it is prescribed for. Guy says Sativex has side effects that are very minor and easily controlled with proper dosing and medical supervision.
In regards to critics’ assertion that Guy exploits prohibition and that if marijuana was totally legal patients would grow and smoke their own cannabis instead of taking Sativex, Guy says bona fide medical marijuana patients, and patients who as yet have never tried marijuana medicines, and those who have tried them and found them inferior, have far different needs and motivations than recreational users or medpot patients who smoke whole marijuana.
“It may be hard for some advocates to believe, but there are millions of people who are quite satisfied with the way their consciousness works, but who want safe, symptomatic relief from a medical condition so they can get on with their life by working, taking care of their children, and being productive members of society,” Guy says. “They aren’t looking to get ‘stoned,’ quite the opposite. Our products will extend the reach of cannabis to people who would never have been comfortable smoking a , or vaporizer.”
To further the goals of people who want to medicate without getting high, Guy’s research team developed precise cannabinoid combinations and dosage methods that allow patients to self-medicate with precise control and with zero risk of harming their lungs.
In order to meet the needs of patients who want cannabinoid medical benefits but don’t want to be stoned, the company’s research has uncovered the inner workings of the subjective feeling of being “high,” and how this feeling is related to medical effects and unwanted side-effects.
Guy says patients are advised to use small amounts of medicine so blood levels of cannabinoids build slowly. Patients seek relief from pain, muscle spasms and other symptoms, but they do not want to be “high,” he says.
During clinical testing, some patients experienced panic when they perceived that they had become “intoxicated.” Other unwanted effects included dizziness, dry mouth, and increased heart rate. Most of these problems are solved when patients self-adjust dosage, or when GW provides gentler formulations or regimens.
“The incidence of side-effects is very minor; cannabis has lived up to its reputation of being one of the safest drugs humans can use,” Guy says. “We have seen our cannabis medicines provide better relief than traditional medicines that are far more dangerous for patients than cannabis ever could be.”
Safety is a key factor in GW’s research and product development, and this has led the company to develop a way to administer cannabinoids without relying on the combustion of cannabis.
“We are not working on only one formulation or only one way of administering cannabis drugs,” Guy said. “Some of our patients will use a pressure-activated oral spray; others will inhale a pure vapor of the drug that is generated without flame. We are perfecting special methods that will ensure the pharmacokinetic properties of cannabinoids, including terpenoids, which are volatile at room temperature. The end result will be that patients and their doctors can exactly monitor the relief and lift they get from our drugs, so that a patient who needs instantaneous relief from an acute symptom will get it, whereas somebody who needs to build their dose gradually so that the relief lasts for several hours will be able to do so as well, all with complete control.”
Guy says his company’s system of sprays, inhalers, and vaporizers will take harm reduction and cannabis delivery to new levels.
“People currently believe that using one of the many models of vaporizer that are on the market will provide them with fully-utilized, totally-clean cannabis vapors, but this is not true,” Guy says. “Cannabinoids cannot be properly vaporized using the kinds of heat sources and chambers that we see on the market right now. There is still some burning of plant material taking place, people are still inhaling carcinogens, and there are irregularities in the quality and design of these vaporizers that prevents people from getting what they think they are getting.”
GW is pleased that its inhaler device has been well-received by regulators, but the company is also developing a medical grade professional vaporizer that will provide truly smoke-free cannabis medicines.
Dr. Guy says all vaporizers currently available are amateur devices that lack the precision and quality needed to truly vaporize target cannabinoids in a 100% safe and effective manner.
“If we create the vaporizer we envisions, patients will be dial in the exact relief they want, push a button, and get a controlled dose that will provide safe, effective relief for a variety of conditions,” Guy promises. “There will be no smoke. Patients will get 98% volatilization of the cannabinoids they need in doses just high enough to achieve the medical effects they seek.”
BIG BAD GW?
When the deal uniting Bayer and GW was announced, GW’s critics jumped all over it, alleging that Bayer is an evil company and that GW’s embrace of Bayer indicated bad intent.
David Malmo-Levine said: “Bayer is arguably the worst corporation on earth. They are the inventors and propagators of Aspirin, Heroin, Mustard Gas, forced labor, the Nazi party, Zyklon B, death labor, Tabun and Sarin nerve gas, parathion, Codex, Cipro, Baycol, Baygon, Fenthion, Baysiston, TDI Olaqunidox, PPA's, PCB's and other such wonders. Bayer has the worst ethical track record of any company this author knows of.”
Dr. Ethan Russo, a long-time cannabis researcher who now works for GW, says Malmo-Levine “seems to be against the entire system of intellectual property, corporations, scientific research, medical progress, and patents.”
“In almost every area of human endeavor, from journalism to medicine to the music industry, individuals and corporations create unique ideas and products and then seek to protect their work through copyrights and patents,” Russo explains. “Even if marijuana was totally legal, most people would not conduct the kind of scientific research that GW is conducting. This research uses cannabinoids to extend lives, cure diseases, and relieve disease symptoms. GW has helped legitimize cannabis medicines, and the company has a right to protect its discoveries and its investments.”
What about Malmo-Levine’s charges that Bayer worked with Hitler’s government and continues to be an unethical company?
“I’m Jewish,” Russo responds, “and I am as horrified by the Holocaust and Hitler as anyone would be, but this is not 1940. Dr. Guy was courted by several pharmaceutical companies, and he chose Bayer as his partner because Bayer is a leading pharmaceutical company committed to getting cannabis medicines to as many people as possible.”
Guy defended his decision to partner with Bayer, and also dismissed charges that his company has created a plant-patents monopoly that will be used against commercial black market marijuana growers, home growers, and medpot growers.
“We will indeed be taking out ‘plant variety rights’ on a number of strains that we developed as part of our R&D program. These rights prevent other parties using our specific strains to produce plant extracts without our permission. GW has only sought patent protection for strains we created; there are plenty of other varieties for people to use, they just can’t use strains we developed,” Guy said. “If people get into trouble for growing cannabis plants, it will be from the police for breaking the law, not from us. If somebody stole our genetic material or our products, that would be breaking the law, but our patents and commercial interests in no way further the drug war.”
Guy allegedly made recent statements that were perceived as threatening by a few Canadian medical marijuana activists who told him they were designing raw plant spray extracts similar to Sativex, but Guy insists that he has no interest in using prohibition to further his marketing or harm people who work on their own with marijuana.
GREEN GOLD RUSH
Whether or not Guy’s intentions, patents and business interests pose imminent monopolistic or plant patent threat to cannabis users and growers in general, there’s evidence that GW is only of many companies seeking to cash in on the cannabis “gold rush.”
For example, Canadian marijuana growers and users who possess coveted Health Canada cultivation and possession licenses are being courted by a myriad of individuals, companies, and advocacy groups, including marijuana fertilizer companies.
When asked about rumors that GW and Bayer were also wooing Canadian licensed medpot patients, Guy and other GW spokespersons acknowledged that his company had contacted “numerous federal exemptees” who “expressed interest in utilizing Sativex as soon as it would be legally available.”
Some Canadian medical marijuana advocacy groups have been contacted by rival companies seeking to co-opt their patients for medical cannabis research. Such medical marijuana advocacy services often advise people how to obtain Health Canada medpot licenses, usually providing them with logistical support, names of sympathetic doctors and other assistance. Some of these service providers charge fees. Others expect would-be licensees to remain under the service’s umbrella when the advocacy service markets them, their licenses, their medical records, or their marijuana to third parties such as pharmaceutical companies or nutrients companies.
In the final analysis, criticisms of Dr. Guy and pharmaceutical marijuana research by marijuana activists contain interesting ironies and inconsistencies.
Recreational marijuana smoking became very popular in Western countries beginning in the 1960’s. Medical marijuana has been increasing in popularity since the 1980’s.
From the 1960’s until the mid-1990’s, the only source for marijuana was Dutch cannabis coffeeshops, and the black market, comprised of smuggling cartels, clandestine dealers, commercial growers, and home growers.
In a reverse echo of Malmo-Levine’s allegation that GW benefits from prohibition, most marijuana industry insiders admit that prohibition is the artificial price support that makes marijuana so profitable for them. If it wasn’t for prohibition, a lot of people would have trouble growing $400 an ounce pot to help pay their mortgages.
The cannabis black market, cultivators, and Dutch coffeeshops could accurately be described as a “monopoly” that has until now controlled the supply and price of marijuana. But now, that underground monopoly has competition. The Dutch government is trying to close cannabis coffeeshops while at the same time growing its own medical marijuana and supplying it to pharmacies. The scheme appears to have failed, because the Dutch government’s cannabis was lower quality and higher priced than coffeeshop cannabis.
Health Canada grew its own marijuana and has been trying to sell it (along with pot seeds) to patients. The scheme appears to have failed because the Canadian government cannabis was low quality, poorly-packaged, and less potent than black market cannabis.
GW Pharmaceuticals and other companies grow marijuana and market its active ingredients to patients. Individuals, compassion clubs and consortiums are trying to cash in on Health Canada medical marijuana licenses by growing and selling large amounts of cannabis. More and more compassion clubs are opening; retailers like Bud Buddy and Jay’s Joints are selling marijuana on the Internet.
Far from being an increasingly monopolistic industry, as Malmo-Levine alleges, it appears that Dr. Guy, Bayer, GW, Solvay, Bud Buddy and others are just part of a growing group of people and companies who are creating a vanguard of anti-monopolistic increased production and expansion of marketing, selling and producing varying cannabis products and methods of cannabis use.
Gone is the day when marijuana users only had two choices: to grow their own cannabis, or procure it on the street corner. Gone is the day when marijuana users could either smoke cannabis or ingest it in home-brewed tinctures, oils, and foods. They now have an ever-wider range of choices for procuring and using marijuana, thanks in part to companies like GW. |
|
| Back to top |
|
 |
Rev. Chazman Cannabis Sacrament Minister


Joined: 15 Nov 2003 Posts: 1403 Location: Illinois - USA
|
Posted: Tue Apr 19, 2005 8:18 pm Post subject: |
|
|
I was talking to somebody recently who had a very clear view on what very likely will happen.
The GW drug being approved is going to be a blow to the Med users. Now they will be able to say to them "here use this official medice that costs you more, or you are breaking the law and go to jail or drug counciling".
Like the drug companys dont already charge poor, sick people to much money already. I believe this is going to be a bad thing. I hope im wrong, but I doubt it.
Peace _________________ I praise good thoughts, good words, and good deeds and those that are to be thought, spoken, and done. I do accept all good thoughts, good words, and good deeds. I do renounce all evil thoughts, evil words, and evil deeds. ---Avesta: Yasna
---------------------------------------------------
Future Servant of Cannatopia ©2004 - ∞ Rev. Chazman all rights reserved |
|
| Back to top |
|
 |
Mystic Power admin THC-Ministry YahooGroup


Joined: 23 Aug 2004 Posts: 3605 Location: Key West
|
Posted: Tue Apr 19, 2005 10:14 pm Post subject: |
|
|
I wish you were wrong, Chaz.
Simply follow the money. It's always the leading indicator of what's what.
Bliss as best y'can,
Ben _________________ "We are the Ones we have been waiting for."
~Hopi Elder ~
"In Lak'ech"
~ Ancient Mayan: "I am another YOU." ~ |
|
| Back to top |
|
 |
Pepper Cannabis Sacrament Minister


Joined: 30 Oct 2003 Posts: 528 Location: Earth
|
Posted: Tue Apr 19, 2005 10:21 pm Post subject: |
|
|
| Here in the US it may take over 15 years and half a billion dollars to approve Sativex. They also have plans for a controlled vaporizer so they can limit the doses electronically. This will satisfy prohibitionists that will worry that someone, somewhere may actually be getting high. It's all about the $$$$. Same as it ever was. |
|
| Back to top |
|
 |
Ferre Cannabis Sacrament Minister.


Joined: 14 Apr 2003 Posts: 7295 Location: Amsterdam
|
Posted: Wed Apr 20, 2005 1:52 am Post subject: |
|
|
| $$$GW$$$ wrote: |
| We are helping thousands and potentially millions of patients. How many patients are our critics helping? |
Well, mr. know-it-all could do a very simple Google search on medical marijuana and find at least two-and-a-half million websies and many million people who do think that the natural way is best for them and they know from experience. _________________ █ Please read the Board Rules and Posting, and you
█ Radio Free Amsterdam
People who know truth, speak truth.
Those who don't, quote scriptures. |
|
| Back to top |
|
 |
Rev. Chazman Cannabis Sacrament Minister


Joined: 15 Nov 2003 Posts: 1403 Location: Illinois - USA
|
Posted: Wed Apr 20, 2005 6:32 am Post subject: |
|
|
| Quote: |
Well, mr. know-it-all could do a very simple Google search on medical marijuana and find at least two-and-a-half million websies and many million people who do think that the natural way is best for them and they know from experience.
|
Well said Brother Ferre, well said.
Peace _________________ I praise good thoughts, good words, and good deeds and those that are to be thought, spoken, and done. I do accept all good thoughts, good words, and good deeds. I do renounce all evil thoughts, evil words, and evil deeds. ---Avesta: Yasna
---------------------------------------------------
Future Servant of Cannatopia ©2004 - ∞ Rev. Chazman all rights reserved |
|
| Back to top |
|
 |
RogerChristie Cannabis Sacrament Minister.

Joined: 16 Feb 2004 Posts: 1098 Location: Hilo, Kingdom of Hawai'i
|
Posted: Wed Apr 20, 2005 11:51 am Post subject: Ding-dong the myth is dead - and you're invited to the party |
|
|
Terrific news on 4-20 the world over!
Hello out there all over the world in cannabisland,
Aloha. This followiing article really hit me hard - in the very best way. Thank you, Rob Kampia. Brilliant! The lie is over.
Canada just certified the FACT that whole plant cannabis IS medicine. The myth is done. Poof! Gone.
Halle-freakin'-lujah! Ding-dong the myth is dead. Which old myth? The wicked myth.
See how you feel when you read it and let me know if it inspires you to a new level of activism as it does for me. Later todayI'm setting-up our traveling ministry booth out in the country right near the erupting volcano lava flow for a 4-20 party and you're all invited! I'm pumped-up about the spring and moon timing and the news and about our ministry solution to this seriously wicked prohibition. I think we're outstanding in what we do and how we do it.
Today is truly a day for celebration! For the cannabis culture. For humanity, and for the future.
No more can ANYONE tell you or me that cannabis does not have "recognized medicinal value". As of today it most certainly does. Thanks to GW and to Canada. You rock!!!!
Much love to you in the present and to everyone else in the future,
Roger
###
The Lesson of Sativex
Posted by CN Staff on April 19, 2005 at 17:51:38 PT
By Rob Kampia, AlterNet
Source: AlterNet
By approving liquid marijuana, the Canadian government has just certified that virtually everything our own government has been telling us about marijuana is wrong.
On April 19, the Canadian government delivered what should be the final blow to the U.S. government's irrational prohibition against the medical use of marijuana. It approved prescription sale of a natural marijuana extract -- for all practical purposes, liquid marijuana -- to treat pain and other symptoms caused by multiple sclerosis.
Sativex, produced by GW Pharmaceuticals in Britain, brings the medical marijuana debate full circle. Though the technology has advanced in 70 years, this product is a direct descendent of the marijuana extracts and tinctures that were a standard part of the medical armamentarium until the late 1930s -- universally recognized as being safe and effective for certain conditions. These products were taken away from patients and doctors as a result of the prohibition on marijuana that began in 1937, despite the public opposition of the American Medical Association.
In short, the Canadian government has just certified that virtually everything our own government has been telling us about marijuana is wrong. In defiance of a large and growing pile of scientific studies, our government still claims that marijuana has no medical value. White House Drug Czar John Walters even compared medical marijuana to "medicinal crack."
Such statements were always scientifically ridiculous, as has been noted by a wide range of authorities, including the American Public Health Association, the American Nurses Association, and the state medical societies of New York, California and Rhode Island, to name just a few. Now, GW Pharmaceuticals' research has definitively put such nonsense to rest.
Make no mistake: Sativex is liquid marijuana. It is nothing like Marinol, the synthetic THC pill sold in the U.S. and sometimes falsely touted as an adequate substitute for marijuana.
Sativex is a whole-plant extract, containing the rich variety of naturally occurring compounds called cannabinoids that are unique to marijuana. It also contains trace elements of other compounds contained in the plant, which scientists believe contribute to its therapeutic value.
On its website, GW Pharmaceuticals explains, "We believe very strongly that many of the advantages of using the whole plant come from the inclusion of other components of cannabis [marijuana]," not just THC. "In the cannabis plant, it appears that some of the components added together give better effect. Some components seem to work to counteract some of the side effects of others, and the whole plant is generally well tolerated by humans."
Sativex is to marijuana as a cup of coffee is to coffee beans. If Sativex is safe and effective, marijuana is safe and effective. And Sativex is safe and effective. Studies have shown significant effect against pain and other symptoms caused by multiple sclerosis and other debilitating conditions. Over 600 patient-years of research have established a remarkable record of safety.
Sativex should certainly be approved in the U.S., but the process may take years -- if it is allowed to happen at all. Sadly, our government's reflexive hostility to the medical use of marijuana shows no sign of abating.
But an even larger issue looms: Now that we know beyond doubt that marijuana is a safe, effective medicine, how long will our government continue to arrest patients who use it?
And even if Sativex is approved here someday, it won't be the answer for every patient now benefiting from medical marijuana. For one thing, it has been clearly shown that different strains of marijuana -- with different blends of cannabinoids -- work better for some conditions and less well for others. Sativex just comes in one formula, and it won't be right for everyone.
And Sativex will be expensive. Will we force patients to buy a pricey pharmaceutical version of a plant they could grow themselves for pennies? At a time when our health care system is drowning in rising costs, that's insane. We could end up with a policy every bit as silly as telling coffee drinkers that they can buy a cappuccino, but they'll be arrested on sight if caught in possession of coffee beans.
The lesson of Sativex is simple: Our government was wrong. Marijuana is medicine, and patients and doctors should be able to use it in whatever form works best for their particular situation.
Rob Kampia is executive director of the Marijuana Policy Project in Washington, DC.
Source: AlterNet (US)
Author: Rob Kampia, AlterNet
Published: April 19, 2005
Copyright: 2005 Independent Media Institute
Contact: letters@alternet.org
Website: http://www.alternet.org/
DL: http://alternet.org/drugreporter/21818/
Related Articles & Web Sites:
Marijuana Policy Project
http://www.mpp.org/
GW Pharmaceuticals
http://www.gwpharm.com/
Canada Approves GWs Cannabis Drug for MS
http://cannabisnews.com/news/thread20541.shtml
GW Clears Cannabis Hurdle
http://cannabisnews.com/news/thread20540.shtml
Cannabis Spray Gets Go-Ahead
http://cannabisnews.com/news/thread20536.shtml
### |
|
| Back to top |
|
 |
sara Cannabis Sacrament Minister


Joined: 29 May 2003 Posts: 448
|
Posted: Wed Apr 20, 2005 1:37 pm Post subject: |
|
|
Ferre, I totally agree , the less processed the better.
why should we buy something we can grow ourselves?
 _________________ “When one is connected above,’’ he said
quietly, “he does not fall below.”
OINK OINK OINK OINK OINK... |
|
| Back to top |
|
 |
Echo Cannabis Sacrament Minister


Joined: 14 Apr 2003 Posts: 1899 Location: England
|
Posted: Wed Apr 20, 2005 8:58 pm Post subject: |
|
|
I am not sure. If it's a medicine, it will be on prescription only, and only the synthetic kind, with trade mark of course. They have the monopoly.
But time will tell. _________________
| Tom Petty wrote: |
Well I know what’s right, I got just one life
In a world that keeps on pushin’ me around
But I’ll stand my ground and I won’t back down
|
|
|
| Back to top |
|
 |
Rev.Holden Greene Cannabis Sacrament Minister


Joined: 25 Feb 2005 Posts: 482 Location: us
|
Posted: Wed Apr 20, 2005 9:46 pm Post subject: |
|
|
i too have mixed feelings about thisit could be just the stepping stone we need or it could be used as an excuse to never allow us to have the whole plant. _________________ "look...the people you are looking for are the people you depend on.we cook your meals , we haul your trash ,we connect your calls, we drive your ambulances,we guard you while you sleep"
Tyler Durdan |
|
| Back to top |
|
 |
RogerChristie Cannabis Sacrament Minister.

Joined: 16 Feb 2004 Posts: 1098 Location: Hilo, Kingdom of Hawai'i
|
Posted: Thu Apr 21, 2005 12:15 am Post subject: Spiritual use is more important than ever! |
|
|
Hello friends,
Aloha. In addition to breaking the myth of 'no medical use', the Sativex decision makes it much more important for us to anchor-in the religious use of sacrament. Those who want the right to grow the plants and use the whole plant for healing might be well advised to do it NOW.
Can you see it? The government allowing ONLY Sativex for those who want 'medical marijuana'? :-{ Get yer prescription from yer doctor and have it filled at the pharmacy for $$$ and go home and shut-up. End of growing your own forever and zero getting high because Sativex has a computer-chip administrator delivery system.
We have another vision; wild and free and growing in your yard or window box or closet. You get as much sacrament as you need to commune with whatever you call God. A religious exemption from the wicked prohibition. Forever free.
Who's going to help the poor and needy? The malnurished and sick? GW? I don't think so. The tree of life is here and ready to serve as it always has. It's obviously (to me and some people) been designed by the Creator to do just that, feed all our hungers. The plant of renown! Mahalo ke akua.
Love forever,
Roger
### |
|
| Back to top |
|
 |
|
|
You cannot post new topics in this forum You cannot reply to topics in this forum You cannot edit your posts in this forum You cannot delete your posts in this forum You cannot vote in polls in this forum
|
|