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Cannabis Munchies Pave Way for New Diet Drug

 
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Ferre
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PostPosted: Fri Jan 28, 2005 11:45 pm    Post subject: Cannabis Munchies Pave Way for New Diet Drug Reply with quote

Here's another interesting research...

Quote:
ACOMPLIA (RIMONABANT) - INVESTIGATIONAL AGENT FOR THE MANAGEMENT OF OBESITY

Under development by Sanofi-Aventis (formerly Sanofi-Synthelabo), Acomplia (rimonabant) is a selective CB1 endocannabinoid receptor antagonist indicated for the treatment of obesity. The drug, which has progressed to phase III development, works by blocking endogenous cannabinoid binding to neuronal CB1 receptors. Activation of these receptors by endoegenous cannabinoids, such as anadamide, increases appetite. It is the only endocannabinoid receptor antagonist in clinical development and thus offers a unique therapeutic approach to appetite control and weight reduction. The drug also has potential as a treatment for smoking cessation because the endocannabinoid system is also involved in the body's response to tobacco dependence.

On the back of successful clinical trials in overweight and obese subjects, Sanofi-Aventis plans to file an NDA with the FDA during the first half of 2005 and, if successful, hopes to bring the drug to market in early 2006.

More:
http://www.drugdevelopment-technology.com/projects/rimonabant/


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Rev. Chazman
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PostPosted: Sun Jan 30, 2005 12:00 am    Post subject: Reply with quote

Interesting... So it blocks certain receptors from allowing cannabinoid's to bind to them... Interesting. Easy to see where this research might lead.

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Lilli
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PostPosted: Sun Jan 30, 2005 12:53 am    Post subject: Reply with quote

Are arm number tattoos next? Then the ovens.
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ReverendCaveGrower
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PostPosted: Sun Jan 30, 2005 1:29 am    Post subject: Reply with quote

Quote:
Rimonabant has been developed from the knowledge that cannabis smokers often experience extreme hunger pangs, which cannabis smokers refer to as 'the munchies'. http://www.drugdevelopment-technology.com/projects/rimonabant/

taken from a caption below a Canabis plant picture on the same page as the article Brother Ferre posted.

so they invented the "anti-munchie" because of pot smokers experience if I read this corectly? I cant wait till it gets FDA aproval and the government has to at least claim 1 instance of Cannabis research being usefull for humanity.

Quote:
The drug also has potential as a treatment for smoking cessation because the endocannabinoid system is also involved in the body's response to tobacco dependence
well duh? we knew that already Smile
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Lilli
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PostPosted: Sun Jan 30, 2005 2:48 am    Post subject: Reply with quote

Thats one diet pill I wont be trying.
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Mystic Power
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Joined: 23 Aug 2004
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Location: Key West

PostPosted: Sun Jan 30, 2005 3:29 am    Post subject: Reply with quote

Lilli wrote:
Thats one diet pill I wont be trying.


Nope. I want my cannabinoid receptors to be oiled and in tip-top working order.

Bliss,
Ben
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Lilli
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PostPosted: Sun Jan 30, 2005 3:33 am    Post subject: Reply with quote

Indeed Much more then I want to be thin. Laughing
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