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Ferre Cannabis Sacrament Minister.


Joined: 14 Apr 2003 Posts: 7295 Location: Amsterdam
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Posted: Wed Jan 18, 2006 7:40 am Post subject: Anti-Obesity diet drug from cannabis works! |
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Anti-Obesity diet drug from cannabis works!
For those whose New Year's resolution was to yet again try to lose those extra kilos help may be at hand in the form of a new wonder drug derived from cannabis.
At first glance cannabis appears an unlikely candidate in the search for a weight-loss miracle drug, but the very same compound which switches off the same brain circuits that make people hungry when they smoke cannabis, could may well be the first blockbuster anti-obesity drug ever.
Analysts are apparently already predicting sales of over $3 billion a year.
Acomplia, or Rimonabant, produced by drug company Sanofi-Aventis could be granted approval by U.S. regulators as soon as next month.
Two other experimental drugs from Arena Pharmaceuticals and Alizyme, which use different methods of action have also produced promising results in clinical trials recently.
All three are part of a new wave of treatments and may mean even bigger profits for pharmaceutical companies.
It is however a high risk area, as slimming pills,historically have a dubious past, mainly due to ineffectiveness and adverse side effects.
Probably one of the most notorious is the diet drug combo "fen-phen," which was linked to heart-valve problems and has cost drug company Wyeth more than $21 billion in litigatious patient claims.
According to analysts there are now 26 new drugs in clinical trials for obesity and a further 32 in the pipeline.
This is along with more than half a dozen diabetes medicines currently being trialed as treatments for weight reduction.
According to World Health Organization (WHO) figures more than 1 billion people in the world are overweight and, if the current trends continues, that number will reach 1.5 billion by the year 2015.
More than 300 million apparently already rank as obese, putting them at substantial risk of heart disease, stroke, type 2 diabetes, respiratory problems and some cancers.
The problem is not confined to developed countries as even in developing countries, including parts of Africa, obesity is on the rise, with the western Pacific islands of Nauru and Tonga currently holding the unenviable position of the highest percentage rates of obesity in the world.
The scale of the problem, indicates that the arrival of new weight-loss drugs cannot come quick enough and will be welcomed.
However in reality, as experts point out, medication will help only a very small minority of patients and will not have an impact on the obesity epidemic.
They say physical activity and diet are far more cost-effective.
However Professor Luc Van Gaal of Belgium's University Hospital Antwerp, the lead investigator for one of the main clinical studies for Acomplia, argues that doctors must accept that dieting and exercise alone often produce disappointing results, leaving patients at risk of falling seriously ill.
Drug therapy, he says is the answer for certain obese patients who are at risk.
There are currently two main obesity medicines on the market, Roche's Xenical, which works by limiting fat absorption, and Abbott's Meridia/Reductil, which suppresses the appetite.
The adverse side effects, have resulted in modest sales of both drugs; Xenical can cause excess gas and oily discharge, while Meridia may increase blood pressure.
GlaxoSmithKline too is hoping for approval from a U.S. panel later this month for its own low-dose, low-side effect version of Xenical to be sold without prescription, but many doubt it will become a major seller.
By contrast, the consensus forecast from analysts for peak sales of Acomplia is $3.1 billion, with some predictions topping $5 billion.
Just how big the drug Acomplia will be will depend on the terms of use that Sanofi agrees with healthcare regulators.
The company is hoping to prove that Acomplia specifically reduces key cardiovascular risk factors, as a simple obesity label may not be enough secure widespread reimbursement from governments and insurers.
With Acomplia too, side effects may be an issue as though patients are reported to have lost around 7 kg (15 lb) in body weight over two years, there are concerns regarding its potential impact on mood.
However the very fact that Sanofi's rivals Merck, Pfizer and Bristol-Myers Squibb are also developing similar cannabinoid receptor blocking drugs, means they think Sanofi is on to something.
http://www.news-medical.net/?id=15421
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zero Cannabis Sacrament Minister


Joined: 28 Nov 2004 Posts: 1579
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Posted: Wed Jan 18, 2006 6:20 pm Post subject: |
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I know of a good diet pill.
It's called physical activity. And it works with no bad side effects. _________________ www.shoutwire.com
www.spikedhumor.com
"I understand that fear is my friend, but not always. Never turn your back on fear. It should always be in front of you, like a thing that might have to be killed." |
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Stokes Cannabis Sacrament Minister


Joined: 28 Nov 2004 Posts: 1426 Location: PA
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Posted: Thu Jan 19, 2006 10:50 pm Post subject: |
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This could also be an interesting investment opportunity.
The symbol is SNY on the New York stock exchange, and here's a link to track it:
http://www.marketwatch.com/news/default.asp?dist=nbs _________________ ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Where love is, there God is also.
-Mahatma Gandhi |
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rainbowwingedfairy getting into high spirits

Joined: 14 Mar 2006 Posts: 1
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Posted: Tue Mar 14, 2006 11:56 pm Post subject: |
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Hello, my doctor is actually thinking of putting me on this drug once it comes out. I am currently on xenical and its working slowly. The only problem about this new one is that its made from cannibus. Does that mean that there's THC in the pill. I mean how safe is this pill; especially for people like me who is a recovering drug addict? I was told by many to do some research on this drug before agreeing to take it. If you have any other information about this, please let me know I would greatly appreciate it.  |
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RevErikM Shaman


Joined: 17 May 2005 Posts: 235
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Posted: Wed Mar 15, 2006 7:28 am Post subject: |
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Rainbow -
If you consider yourself to be a recovering drug addict, then your usage of the Sacred Plants was probably intended to subdue something that bothered you about yourself.
As far as addiction and drugs go, nothing is worse than the stuff pumped out by Big Rx.
There's nothing wrong with enjoying time with the Sacred Teacher Plants; most of us here consider it to be spiritually nourishing and physically healing. A lot of people paint it red though - and a lot of people will try to get you to base everything you do on procuring and using more and more of the plant to subdue how you feel about yourself rather than face it and overcome it; this is in my opinion a crime against the nature of the Sacred Teachers and the people who are taught to use them that way. Like everything, there's a constructive use and a destructive use.
The responsibility for everything lies with you, and the best way to change something that seems fixed and immobile is to change the way you view it. In my experience, there is no power higher than the self, and the self is only as strong as your perspective of it. I used to go to NA and AA meetings with a friend, and I was completely confounded because of the whole "higher power" and "always in recovery" bit; I explained my views to them and they told me I had to give up responsibility for my own actions and lay my fate in the hands of a "higher power," even if I chose for my higher power to be a door knob. As for willpower, they told me something about seeing how much willful control over a bowel movement I had and compared "drug" use to that.
I don't think that you or anyone else is an addict or suffering from an unbearable weight pressed upon them by drugs; I think the illness of the situation is a lack of perspective-shift, which is the purpose of using the Sacred Teachers in the first place. If you use them to shift your perspective to blindness over your problems, you create more problems, thus needing more of the Sacred Teachers to bury those problems. If you use them to face your problems and bring them to the surface to accept them, the opposite occurs.
Then again, I'm a Shaman, and that's how the plants have told me themselves to use them.
I hope I've helped you, but ultimately, I can't show anything to anyone that they can't already see.
Good luck! _________________ Experience things for yourself.
Please check out my book at:
http://www.lulu.com/content/151260 |
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RogerChristie Cannabis Sacrament Minister.

Joined: 16 Feb 2004 Posts: 1098 Location: Hilo, Kingdom of Hawai'i
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Posted: Wed Mar 15, 2006 10:39 am Post subject: Stop and think - and please don't take this drug. |
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Hello friends of Cannabis,
Aloha. Please consider this; this new drug, "switches off the same brain circuits that make people hungry when they smoke cannabis." As far as I know, it also switches-off the same brain circuits that make people HIGH!
'Switches off brain circuits when they smoke Cannabis.' You don't really want a big pharmaceutical company's mystery pill or powder switching-off your brain circuits, the Cannabis receptors, do you?
For all of us who enjoy the feelings and the high of Cannabis use, the connection to God and nature and all that is, the sights, sounds and smells, the heightened sensations and imaginations this mysterious herb imparts within us, please stay away from this DRUG.
The U.S. government is constantly researching Cannabis-blocking DRUGS for the treatment of un-repentent Cannabis enjoyers. Guess which DRUG works best, so far? As far as I know, it's the diet drug mentioned above.
Please don't take this, or any 'cannabinoid-blocking drugs' if you want to keep enjoying the benefits of Cannabis.
All the very best to you,
Roger
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Pepper Cannabis Sacrament Minister


Joined: 30 Oct 2003 Posts: 528 Location: Earth
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Posted: Wed Mar 15, 2006 1:28 pm Post subject: |
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These drugs that block CB1 receptors also block the body's natural reward system. This means it can affect mood, memory, appetite, and pain perception.
The major side effect they claim are nausea and dizzyness. Clinical depression is a side effect of these drugs and this information is being suppressed.
The drug must be taken for life to keep the weight off. |
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Mystic Power admin THC-Ministry YahooGroup


Joined: 23 Aug 2004 Posts: 3605 Location: Key West
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Posted: Wed Mar 15, 2006 11:50 pm Post subject: |
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I think I'll continue to walk with Cannabis in it's natural form.
Of course, as clinical studies reveal, this may lead to eating raw cookie dough over the sink at midnight...
...not sure how this will effect the weight-loss thing. I'll study it further and get back to ya.
Follow Your Bliss,
Ben _________________ "We are the Ones we have been waiting for."
~Hopi Elder ~
"In Lak'ech"
~ Ancient Mayan: "I am another YOU." ~ |
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IntrepidEZJ Cannabis Sacrament Minister

Joined: 19 Mar 2006 Posts: 381
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Posted: Mon Mar 27, 2006 11:51 pm Post subject: |
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I posted in another thread that I would not trust Bayer, because they are one of 3 companies that emerged unscathed from the Nurembourg Tribunals after the fall of Nazi Germany.
Of those other 3, Aventis was number 2.
You better listen to Roger folks. |
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Ferengi420 Cannabis Sacrament Minister


Joined: 30 May 2004 Posts: 9 Location: Far North Queensland
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Posted: Tue Mar 28, 2006 1:16 pm Post subject: |
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If by taking these diet pills you couldnt get stoned. Then I think they have there merit, for people that use cannabis and prefer not to get high.
EG- M.S patients.
 _________________ Cannabis |
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Slide Cannabis Sacrament Minister


Joined: 11 Mar 2004 Posts: 339
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Posted: Tue Mar 28, 2006 1:30 pm Post subject: |
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cannabis receptors play wider role and an important role other than just making you hungry. The body's natural cannaboids help regulate many important functions.
The impaired ability to create and use your own, or to supplement it with natural plants, will have horrible effects on the users of this DRUG. |
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